Postdoctoral Scholar, Radiation Oncology, Cancer Biology and FLASH/Ultra-High Dose Rate Radiotherapy Research Position Overview School / Campus / College: School of Medicine Organization: Radiation Oncology Title: Postdoctoral Scholar, Radiation Oncology, Cancer Biology and FLASH/Ultra-High Dose Rate Radiotherapy Research Position Details Position Description The University of Washington (UW) Department of Radiation
Oncology invites applications for a Postdoctoral Scholar who will focus on research in cancer biology and FLASH/ultra-high dose rate radiotherapy (UHDR-RT). This position offers an exceptional opportunity for a motivated PhD or MD/PhD scientist to advance the biological and translational foundations of next-generation radiotherapy. Fred Hutch and UW have a rich and pioneering legacy in radiation oncology and particle
therapy research. UW Medicine was among the first institutions in the United States to establish a hospital-based proton therapy center and has contributed foundational work in proton and neutron therapy physics, clinical implementation, and radiobiology. These efforts, coupled with Fred Hutch’s internationally recognized expertise in human biology, transplantation, and tumor immunology, have consistently placed
Seattle at the forefront of precision radiation sciences. Building on this tradition, the program is now positioned to lead the next era of FLASH and ultra-high dose rate radiotherapy research, leveraging decades of excellence in both biological discovery and technological innovation. Position Overview The successful applicant will join a multidisciplinary environment at Fred Hutchinson Cancer Center and UW Medicine,
working with expert faculty in radiation biology, cancer metabolism, DNA damage response, tumor microenvironment, and immuno-oncology. The postdoctoral scholar will pursue an independent yet mentored project with a specific emphasis on the mechanistic underpinnings of FLASH/ultra-high dose rate radiotherapy and its potential to improve therapeutic index in cancer care. Projects may span: Mechanistic laboratory
research (e.g., tumor and normal tissue response, DNA repair, oxidative stress, metabolic rewiring, and immune modulation in FLASH/UHDR-RT). Preclinical model development (orthotopic murine systems, patient-derived xenografts, 3D organoids). Correlative studies linking preclinical discoveries to clinical trials in radiation oncology. Innovative imaging and biomarker development to track response to ultra-high dose
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