The Palomero Laboratory, led by Dr. Teresa Palomero (Professor of Pathology and Cell Biology, Institute for Cancer Genetics, Columbia University), is a basic/translational research group investigating the molecular genetics and epigenetic mechanisms mediating malignant transformation in T-cell malignancies, including T-cell acute lymphoblastic leukemia (T-ALL) and peripheral T-cell lymphomas (PTCL), using human and
murine models. Our small group is dynamic and collaborative, integrated by researchers with diverse backgrounds and expertise. For additional information and a list of publications, please visit our website: Palomero Lab . Current open areas of research include genomic, transcriptomic and single-cell approaches towards identification of mechanisms of lymphoma and leukemia transformation; interactions between tumor
cells and the tumor microenvironment; mechanistic (genetic and biochemical) analyses of lymphoma oncogenes and tumor suppressors; and the identification and evaluation of experimental therapeutics targeting vulnerabilities in human mature T-cell malignancies. The lab is located in the Irving Cancer Research Center on the Columbia University Irving Medical Center campus in Washington Heights, New York City, and has
full access to Columbia's shared core facilities, including flow cytometry, single-cell genomics, molecular pathology and animal husbandry cores. Position Overview We are seeking a highly motivated Postdoctoral Research Scientist to join our team studying the genetics and mechanisms of T-cell leukemia and lymphoma. The successful candidate will design and execute experiments using mouse models of T-cell malignancy,
human patient sample analysis, and flow cytometry- and single-cell-based immune profiling, with a focus on tumor microenvironment interactions and the evaluation of experimental therapeutics, working closely with lab members and collaborators across the Institute for Cancer Genetics and the Herbert Irving Comprehensive Cance
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