Location SAINT LOUIS, MO 63110

 Position Summary Postdoctoral Research (Scholar or Associate) Position Open in the Jaebok Choi Lab in Department of Medicine, Division of Oncology. Area of expertise: Transplant Immunology focused on T cells. The Choi Lab is seeking a postdoctoral researcher to work on T cell biology in mouse models of diseases, including, but not limited to, graft-vs-host disease (GvHD),
inflammatory bowel disease (IBD), and/or experimental autoimmune encephalomyelitis (EAE). Using unbiased genome-wide CRISPR/Cas9 guide RNA library screens and whole kinome analyses, we have identified promising novel therapeutic targets such as VLDLR, GAS6/TAM, and PKN1 whose targeting may separate the inflammatory diseases from the beneficial healthy immune responses, such as graft-vs-leukemia/tumor effects,
anti-tumor and anti-infection responses. For translational approaches, the postdoctoral researcher may occasionally analyze human patient samples. In addition to high-quality research facilities, career and professional development training for postdoctoral researchers is provided through the Career Center, Teaching Center, Office of Postdoctoral Affairs, and campus groups. Job Description Primary Duties &
Responsibilities: Information on being a postdoc at WashU in St. Louis can be found at https://postdoc.wustl.edu/prospective-postdocs-2/ . Please see departmental websites for the more information at https://profiles.wustl.edu/en/persons/jaebok-choi/ and https://oncology.wustl.edu/people/jaebok-choi-phd/ . Trains under the supervision of a faculty mentor including (but not limited to): Manages their own project,
which should lead to a first author publication. Develops expertise in T cell biology, mouse models of GvHD/GvL, IBD, or EAE, CRISPR/Cas9 guide RNA library screening, bioluminescence imaging, intestinal organoids, and multicolor flow cytometry. Develops proficiency in career skills, including writing, public speaking, networking, and critical evaluation of scientific literature. Presents scientific work both inside
and outside the University with excellent oral communication skills. Assists with grant preparation and reporting. Prepares and submits papers on research. Assists in the design of research experiments. Evaluates research findings and assists in the reporting of the results. Conscientious discharge of their research responsibilities. Maintains conformity with ethical standards in research. Maintains compliance with
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