Postdoctoral Fellow Kettenbach Lab – Geisel School of Medicine at Dartmouth, Lebanon, NH The Kettenbach Lab ( https://kettenbachlab.org ) at the Geisel School of Medicine at Dartmouth is seeking a Postdoctoral Fellow to join our team studying Phosphoprotein Phosphatase in health and disease. Our lab investigates the molecular mechanisms underlying phosphorylation-dependent signaling in normal cells and tissues, as
well as in disease. Protein phosphorylation is an essential regulatory mechanism that controls nearly all aspects of cell division and is commonly dysregulated in human cancers. Protein kinases and phosphatases are the direct effectors of phosphorylation signaling. We are using state-of-the-art approaches in proteomics, biochemistry, and cell biology to functionally dissect signaling networks regulated by the
interplay between protein kinases and phosphatases. We are developing methods for quantitative mass spectrometry-based proteomics and phosphoproteomics to gain novel insights into these complex signaling networks by determining dynamic changes in protein expression, protein-protein interactions, and post-translational modifications. We foster a collegial, inclusive lab culture built on curiosity, scientific rigor,
and teamwork. Mentorship and career development are tailored to each trainee's goals. The candidate will be supported in leading their own projects, pursuing new research directions, applying for fellowships, presenting at scientific meetings, and preparing for a range of career paths. Key Responsibilities Under the direction of the Principal Investigator, the candidate is expected to lead experimental projects to
dissect the role of phosphoprotein phosphatases in health and disease by using and developing quantitative mass spectrometry-based proteomics and phosphoproteomics approaches. Keep meticulous laboratory records and communicate effectively and transparently about experiments. Train and supervise students in laboratory procedures. St
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